Meselson & Stahl, The Semi-Conservative Replication of DNA In 1958, Matthew Meselson and Frank Stahl published the “most beautiful experiment”, where they demonstrated that DNA undergoes semi-conservative replication. In this video, we describe the experiments that lead to this discovery and why understanding how DNA replicates is so important. This video is a complement to…
The Cat Who Broke his Sweet Tooth
Exploring taste receptors in cats and humans. In collaboration with Carry The One Radio, we have produced a short video explaining why cats cannot taste sweet foods. Learn what cats and dolphins have in common that makes them fundamentally different from humans when it comes to taste and food preferences. Listen to short interviews with…
Our Genome in a Circle
Advanced genetics topic: Learn a new way of visualizing complex genetic patterns using Circos. Thanks to this method, it is easy to compare patterns of genomic changes in health and disease to decipher clues such as driver mutations in cancer development. This video was produced in collaboration with SeventyK.
Funding Basic Science to Revolutionize Medicine
Youreka Science Founder Wins FASEB “Stand Up For Science” Video Contest and DeBakey Science Journalism Award for best viral video! Learn how the simple biological finding that bacteria can cut DNA lead to a scientific revolution that is now used in thousands of labs around the world and in the production of insulin for diabetic…
What is ALD? Adrenoleukodystrophy explained
What is ALD? Adrenoleukodystrophy is a devastating genetic disease that affects the myelin around neurons in the brain and spinal cord. Learn the biology underlying the disease and what potential treatments may come from ALD research. This video was produced in collaboration with ALD Connect (www.aldconnect.org)
Colon Cancer: Signed, Sealed, Resected
Discovering the genetic clues within colorectal cancers. Colorectal cancer is the second leading cause of cancer deaths. It can be lethal if the tumors come back after surgery, which we call relapse. Scientists have looked at the tumor DNA to discover clues that can predict the likelihood of colorectal cancer relapse after surgery. Find out…
Shedding Light on the DNA’s Dark Matter
What explains 74% of skin cancers. Scientists are beginning to discover what is hidden in 99% of our DNA. And it turns out this new information may redefine the way we think of cancer development. These scientists have discovered an important role for a protein involved in extending lifespan of mice and cells in driving…
He’s Got His Father’s Eyes and His Mother’s Mutations
Discovering an important source of genetic variation. This great article reveals new insights into the origin of our genetic variation: What makes us different from our parents and neighbors and what does this mean for our health? Original Article: Rate of de novo mutations and the importance of father’s age to disease risk. Kong et…
Pay Attention to the Passengers
Cancer passenger deletions provide new therapeutic target. Cancer is complex and so is our DNA. So when it comes to genetic mutations driving cancer, the story is even more sophisticated. But with sophistication comes ideas! Learn how we can take advantage of passenger deletions to specifically target cancer cells at their most vulnerable point! Original…
Stopping the Clock
What if we could stop aging? Or even reverse it? Scientists are discovering new ways to apply gene therapy to the question of longevity in a mouse model! Original Article: Telomerase Gene Therapy in Adult and Old Mice Delays Aging and Increases Longevity Without Increasing Cancer. Bernades de Jesus et al. EMBO Molecular Medicine, 2010….